Nontuberculous mycobacteria-associated lung disease in hospitalized persons, United States, 1998-2005

Abstract

The prevalence and trends of pulmonary nontuberculous mycobacteria (NTM)-associated hospitalizations in the United States were estimated using national hospital discharge data. Records were extracted for all persons with a pulmonary NTM International Classification of Diseases code (031.0) hospitalized in the 11 states with continuous data available from 1998 through 2005. Prevalence was calculated using US census data. Pulmonary NTM hospitalizations (031.0) increased significantly with age among both sexes: relative prevalence for persons 70-79 years of age compared with those 40-49 years of age was 15/100,000 for women (9.4 vs. 0.6) and 9/100,000 for men (7.6 vs. 0.83). Annual prevalence increased significantly among men and women in Florida (3.2%/year and 6.5%/year, respectively) and among women in New York (4.6%/year) with no significant changes in California. The prevalence of pulmonary NTM-associated hospitalizations is increasing in selected geographic areas of the United States.

Figure 1

Average annual prevalence of non-AIDS pulmonary nontuberculous mycobacteria–associated hospitalizations by age group and sex, Healthcare Cost and Utilization Project state inpatient databases, USA, 1998–2005.

Figure 2

Prevalence of non-AIDS pulmonary nontuberculous mycobacteria–associated hospitalizations among men by age group and year, Healthcare Cost and Utilization Project (HCUP) state inpatient databases, USA, 1998–2005.

Figure 3

Prevalence of non-AIDS pulmonary nontuberculous mycobacteria–associated hospitalizations among women by age group and year, Healthcare Cost and Utilization Project (HCUP) state inpatient databases, USA, 1998–2005.

Figure 4

Age-adjusted prevalence of non-AIDS pulmonary nontuberculous mycobacteria–associated hospitalizations among men, California (CA), Florida (FL), and New York (NY), USA, Healthcare Cost and Utilization Project state inpatient databases, 1998–2005.

Figure 5

Age-adjusted prevalence of non-AIDS pulmonary nontuberculous mycobacteria–associated hospitalizations among women, California (CA), Florida (FL), and New York (NY), USA, Healthcare Cost and Utilization Project state inpatient databases, 1998–2005.

Figure 6

Prevalence of chronic obstructive pulmonary disease as a secondary diagnosis by age group and sex when non-AIDS pulmonary nontuberculous mycobacteria is the primary diagnosis, Healthcare Cost and Utilization Project state inpatient databases, USA, 1998–2005.

Figure 7

Prevalence of bronchiectasis as a secondary diagnosis by age group and sex when non-AIDS pulmonary nontuberculous mycobacteria is the primary diagnosis, Healthcare Cost and Utilization Project state inpatient databases, USA, 1998–2005.