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. 2009 Oct;15(10):1582-9.
doi: 10.3201/eid1510.080877.

Community-associated methicillin-resistant Staphylococcus aureus, Iowa, USA

Philip Van De Griend  1 , Loreen A Herwaldt, Bret Alvis, Mary DeMartino, Kristopher Heilmann, Gary Doern, Patricia Winokur, Diana DeSalvo Vonstein, Daniel Diekema
Affiliations

Community-associated methicillin-resistant Staphylococcus aureus, Iowa, USA

Philip Van De Griend et al. Emerg Infect Dis. 2009 Oct.

Abstract

We performed antimicrobial drug susceptibility testing and molecular typing on invasive methicillin-resistant Staphylococcus aureus (MRSA) isolates (n = 1,666) submitted to the University of Iowa Hygienic Laboratory during 1999-2006 as part of a statewide surveillance system. All USA300 and USA400 isolates were resistant to <or=3 non-beta-lactam antimicrobial drug classes. The proportion of MRSA isolates from invasive infections that were either USA300 or USA400 increased significantly from 1999-2005 through 2006 (p<0.0001). During 2006, the incidence of invasive community-associated (CA)-MRSA infections was highest in the summer (p = 0.0004). Age <69 years was associated with an increased risk for invasive CA-MRSA infection (odds ratio [OR] 5.1, 95% confidence interval [CI] 2.06-12.64), and hospital exposure was associated with decreased risk (OR 0.07, 95% CI 0.01-0.51).

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Figures

Figure 1
Figure 1
Number of invasive methicillin-resistant Staphylococcus aureus isolates submitted in Iowa, USA, 1999–2006. CA-MRSA, community-associated MRSA.
Figure 2
Figure 2
Number of USA300/400 methicillin-resistant Staphylococcus aureus (MRSA) isolates submitted by season, Iowa, USA, 2006.
See this image and copyright information in PMC

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