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. 2009 Nov 3;101(9):1630-4.
doi: 10.1038/sj.bjc.6605337. Epub 2009 Sep 29.

Alcohol intake and risk of thyroid cancer in the NIH-AARP Diet and Health Study

C L Meinhold  1 , Y Park, R Z Stolzenberg-Solomon, A R Hollenbeck, A Schatzkin, A Berrington de Gonzalez
Affiliations

Alcohol intake and risk of thyroid cancer in the NIH-AARP Diet and Health Study

C L Meinhold et al. Br J Cancer. .

Abstract

Background: Certain studies suggest that alcohol may reduce the risk of thyroid cancer in women, but the effect in men remains unclear.

Methods: We analysed the association between alcohol and thyroid cancer in a large (n=490 159) prospective NIH-AARP Diet and Health Study with self-reported beer, wine, and liquor intakes.

Results: Over 7.5 years of follow-up (median), 170 men and 200 women developed thyroid cancer. Overall, the thyroid cancer risk decreased with greater alcohol consumption (> or =2 drinks per day vs none, relative risk=0.57, 95% CI 0.36-0.89, P-trend=0.01).

Conclusions: These results suggest a potential protective role for alcohol consumption in thyroid cancer.

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Figures

Figure 1
Figure 1
Associations between alcohol intake (⩾1 drink per day vs none) and thyroid cancer risk by sex, smoking status, body mass index (BMI), and histological type, using the NIH-AARP Diet and Health Study (n=490 159). The models were adjusted for age, sex, race (non-Hispanic white, non-Hispanic black, other, or missing), education (less than high school, high school graduate, some college, college graduate, or missing), smoking status (never, former, current, or missing), body mass index (BMI<25.25−29.9, ⩾30 kg m−2 or missing), and family history of cancer (no, yes, or missing).
See this image and copyright information in PMC

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