Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Nov 3;101(9):1635-40.
doi: 10.1038/sj.bjc.6605351. Epub 2009 Sep 29.

Human papillomavirus infection in Beijing, People's Republic of China: a population-based study

R Zhao  1 , W Y Zhang, M H Wu, S W Zhang, J Pan, L Zhu, Y P Zhang, H Li, Y S Gu, X Z Liu
Affiliations

Human papillomavirus infection in Beijing, People's Republic of China: a population-based study

R Zhao et al. Br J Cancer. .

Abstract

Background: No recent data exist on human papillomavirus (HPV) infection in Beijing, People's Republic of China.

Materials and method: We interviewed and examined a representative, randomly selected sample of 5552 sexually active women aged 25-54 years. Cervical cell samples were analysed for HPV DNA by a MY09/11-based PCR assay.

Results: Human papillomavirus prevalence was 6.7% overall and 4.8% among women without cervical abnormalities. Of the 21 subtypes identified, HPV16 was the commonest type (2.6% overall; 39.1% of HPV-positive women), followed by HPV 58 (1.0%), 33 (0.8%), 43 (0.7%) and 56 (0.7%). High-risk HPV types predominated in all age groups. Human papillomavirus prevalence was highest in young to middle-aged women. Marital status, number of husband's sexual partners, age at sexual debut and nulligravidity were all associated with being HPV positive.

Conclusions: In our survey, HPV 16, HPV 58 and HPV 33 were the most prevalent HPV types in Beijing, indicating the potential for the prophylactic HPV 16/18 vaccine in China.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Age-specific prevalence of human papillomavirus DNA and corresponding 95% confidence interval (Beijing, China, 2008).
Figure 2
Figure 2
Percentage of women in each age group infected with single and multiple human papillomavirus.
Figure 3
Figure 3
Human papillomavirus type-specific distribution and pathology grade (Beijing, China, 2008).
See this image and copyright information in PMC

References

    1. Bao YP, Li N, Smith JS, Qiao YL (2008a) Human papillomavirus type-distribution in the cervix of Chinese women: a meta-analysis. Int J STD AIDS 19: 106–111 - PubMed
    1. Bao YP, Li N, Smith JS, Qiao YL (2008b) Human papillomavirus type distribution in women from Asia: a meta-analysis. Int J Gynecol Cancer 18: 71–79 - PubMed
    1. Bosch FX, Burchell AN, Schiffman M, Giuliano AR, de Sanjose S, Bruni L, Tortolero-Luna G, Kjaer SK, Munoz N (2008) Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia. Vaccine 26(Suppl 10): K1–K16 - PubMed
    1. Bosch FX, Lorincz A, Munoz N, Meijer CJ, Shah KV (2002) The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 55: 244–265 - PMC - PubMed
    1. Cai HB, Ding XH, Chen CC (2009) Prevalence of single and multiple human papillomavirus types in cervical cancer and precursor lesions in Hubei, China. Oncology 76: 157–161 - PubMed

Publication types