Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jan;38(Database issue):D586-92.
doi: 10.1093/nar/gkp880. Epub 2009 Oct 27.

The Mouse Genome Database: enhancements and updates

Carol J Bult  1 , James A Kadin, Joel E Richardson, Judith A Blake, Janan T Eppig; Mouse Genome Database Group
Affiliations

The Mouse Genome Database: enhancements and updates

Carol J Bult et al. Nucleic Acids Res. 2010 Jan.

Abstract

The Mouse Genome Database (MGD) is a major component of the Mouse Genome Informatics (MGI, http://www.informatics.jax.org/) database resource and serves as the primary community model organism database for the laboratory mouse. MGD is the authoritative source for mouse gene, allele and strain nomenclature and for phenotype and functional annotations of mouse genes. MGD contains comprehensive data and information related to mouse genes and their functions, standardized descriptions of mouse phenotypes, extensive integration of DNA and protein sequence data, normalized representation of genome and genome variant information including comparative data on mammalian genes. Data for MGD are obtained from diverse sources including manual curation of the biomedical literature and direct contributions from individual investigator's laboratories and major informatics resource centers, such as Ensembl, UniProt and NCBI. MGD collaborates with the bioinformatics community on the development and use of biomedical ontologies such as the Gene Ontology and the Mammalian Phenotype Ontology. Recent improvements in MGD described here includes integration of mouse gene trap allele and sequence data, integration of gene targeting information from the International Knockout Mouse Consortium, deployment of an MGI Biomart, and enhancements to our batch query capability for customized data access and retrieval.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Screen shot demonstrating the new gene trap allele detail page for a BayGenomics gene trap in the Alms1 gene.
Figure 2.
Figure 2.
Screen shot of MGI GBrowse showing gene traps and gene targeting projects from the IKMC. Figure shows mouse chromosome 6 region 85577061-85692283 (NCBI Build 37).
Figure 3.
Figure 3.
Screen shots of the MGI BioMart. To create a data set in BioMart users select the database of interest (A), select the attributes they wish to include in their results (B), and save the results in one of several possible format (C). Sets of results can be refined iteratively and can be combined with data from external BioMarts.
See this image and copyright information in PMC

References

    1. Blake JA, Bult CJ, Eppig JT, Kadin JA, Richardson JE the Mouse Genome Database Group. The Mouse Genome Database genotypes::phenotypes. Nucleic Acids Res. 2009;37:D712–D719. - PMC - PubMed
    1. Bult CJ, Eppig JT, Kadin JA, Richardson JE, Blake JA the Mouse Genome Database Group. The Mouse Genome Database (MGD): mouse biology and model systems. Nucleic Acids Res. 2008;36:D724–D728. - PMC - PubMed
    1. Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE the Mouse Genome Database Group. The Mouse Genome Database (MGD): new features facilitating a model system. Nucleic Acids Res. 2007;35:D630–D637. - PMC - PubMed
    1. Smith CM, Finger JH, Hayamizu TF, McCright IJ, Eppig JT, Kadin JA, Richardson JE, Ringwald M. The mouse Gene Expression Database (GXD): 2007 update. Nucleic Acids Res. 2007;35:D618–D623. - PMC - PubMed
    1. Krupke DM, Begley DA, Sundberg JP, Bult CJ, Eppig JT. The Mouse Tumor Biology database. Nat. Rev. Cancer. 2008;8:459–465. - PMC - PubMed

Publication types