Ketorolac: an injectable NSAID
- PMID: 1986489
Ketorolac: an injectable NSAID
Abstract
Ketorolac tromethamine is the first injectable nonsteroidal anti-inflammatory drug approved for the management of acute pain. In analgesic potency and ability to relieve postoperative pain, it is comparable to morphine. The advantages of ketorolac over opiates are the absence of respiratory depression and lack of drug abuse potential. Ketorolac has a longer duration of action than morphine, but it has less effect on the central nervous system. Ketorolac should not be used for obstetric analgesia.
Similar articles
-
Ketorolac, an injectable nonnarcotic analgesic.Clin Pharm. 1990 Dec;9(12):921-35. Clin Pharm. 1990. PMID: 2292174 Review.
-
Ketorolac: a new parenteral nonsteroidal anti-inflammatory drug for postoperative pain management.J Post Anesth Nurs. 1992 Aug;7(4):238-42. J Post Anesth Nurs. 1992. PMID: 1494990
-
Parenteral ketorolac: opiate-sparing effect and lack of cardiorespiratory depression in the perioperative patient.Pharmacotherapy. 1990;10(6 ( Pt 2)):127S-131S. Pharmacotherapy. 1990. PMID: 2127959 Clinical Trial.
-
Ketorolac tromethamine: a nonsteroidal anti-inflammatory analgesic used as an adjunct for general anesthesia.AANA J. 1992 Jun;60(3):304-7. AANA J. 1992. PMID: 1632159
-
Ketorolac tromethamine.Conn Med. 1991 May;55(5):288-90. Conn Med. 1991. PMID: 1860314 Review. No abstract available.
Cited by
-
Effect of pretreatment with ketorolac tromethamine on operative pain during periodontal surgery: A case-control study.J Indian Soc Periodontol. 2011 Jan;15(1):55-8. doi: 10.4103/0972-124X.82274. J Indian Soc Periodontol. 2011. PMID: 21772723 Free PMC article.
-
Mucosal co-delivery of ketorolac and lidocaine using polymeric wafers for dental application.Drug Deliv. 2018 Nov;25(1):35-42. doi: 10.1080/10717544.2017.1413445. Drug Deliv. 2018. PMID: 29226726 Free PMC article.