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. 2009 Nov 21:(43):6640-2.
doi: 10.1039/b911559e. Epub 2009 Sep 17.

Detection of DNA using bioactive paper strips

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Detection of DNA using bioactive paper strips

M Monsur Ali et al. Chem Commun (Camb). .

Abstract

Paper strips containing DNA-conjugated microgels (MG) are used to achieve sensitive DNA detection in three steps: target DNA promoted ligation of a DNA primer to the MG-bound DNA, rolling circle amplification (RCA) between the primer and a circle DNA, and hybridization of the RCA products and a fluorescent DNA probe.

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