Detection of DNA using bioactive paper strips
- PMID: 19865676
- DOI: 10.1039/b911559e
Detection of DNA using bioactive paper strips
Abstract
Paper strips containing DNA-conjugated microgels (MG) are used to achieve sensitive DNA detection in three steps: target DNA promoted ligation of a DNA primer to the MG-bound DNA, rolling circle amplification (RCA) between the primer and a circle DNA, and hybridization of the RCA products and a fluorescent DNA probe.
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