Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1920 Mar 31;31(4):403-43.
doi: 10.1084/jem.31.4.403.

STUDIES ON EXPERIMENTAL PNEUMONIA : I. PRODUCTION OF PNEUMOCOCCUS LOBAR PNEUMONIA IN MONKEYS

F G Blake  1 , R L Cecil
Affiliations

STUDIES ON EXPERIMENTAL PNEUMONIA : I. PRODUCTION OF PNEUMOCOCCUS LOBAR PNEUMONIA IN MONKEYS

F G Blake et al. J Exp Med. .

Abstract

1. Lobar pneumonia has been consistently produced in normal monkeys by the intratracheal injection of minute amounts of pneumococcus culture. 2. The disease produced has been shown to be clinically identical with lobar pneumonia in man. 3. Lobar pneumonia has been produced in the monkey in one instance by experimental contact infection. 4. Normal monkeys inoculated in the nose and throat with large amounts of pneumococcus culture have failed to develop lobar pneumonia though carrying the organism in their mouths for at least a month. They have likewise failed to show any evidence of upper respiratory tract infection. 5. Monkeys inoculated subcutaneously or intravenously with pneumococcus culture have in no instance developed pneumonia, but have either died of pneumococcus septicemia or recovered without localization of the infection in the lungs.

PubMed Disclaimer

References

    1. J Exp Med. 1912 Feb 1;15(2):133-48 - PubMed
    1. J Exp Med. 1915 Dec 1;22(6):747-56 - PubMed
    1. J Exp Med. 1916 Dec 1;24(6):651-70 - PubMed
    1. J Exp Med. 1919 Oct 1;30(4):379-88 - PubMed