Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1924 Nov 30;40(6):743-52.
doi: 10.1084/jem.40.6.743.

PATHOLOGY OF EXPERIMENTAL PNEUMOCOCCUS PNEUMONIA IN MICE

A Branch  1 , E G Stillman
Affiliations

PATHOLOGY OF EXPERIMENTAL PNEUMOCOCCUS PNEUMONIA IN MICE

A Branch et al. J Exp Med. .

Abstract

1. The administration of alcohol produces no evident histological changes in the lungs of mice. 2. Following inhalations of pneumococci the organisms are not visible histologically in the lungs of mice either in the bronchi or alveoli. 3. In partially immunized mice which have been exposed to a pneumococcus spray while alcoholized, true lobar pneumonia not infrequently develops. 4. The primary lesion of such lobar pneumonia in mice is an interstitial inflammation of the alveolar wall and the infection spreads in the interstitial tissue like a cellulitis. 5. A tentative explanation of the "lobar" distribution of pneumococcus pneumonia is offered.

PubMed Disclaimer

References

    1. J Exp Med. 1920 Mar 31;31(4):445-74 - PubMed
    1. J Exp Med. 1924 Sep 30;40(4):567-74 - PubMed
    1. J Exp Med. 1924 Nov 30;40(6):733-42 - PubMed