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. 1924 Nov 30;40(6):761-72.
doi: 10.1084/jem.40.6.761.

THE PRODUCTION OF AN EXOTOXIN BY CERTAIN STRAINS OF STAPHYLOCOCCUS AUREUS

J T Parker  1
Affiliations

THE PRODUCTION OF AN EXOTOXIN BY CERTAIN STRAINS OF STAPHYLOCOCCUS AUREUS

J T Parker. J Exp Med. .

Abstract

1. The sterile Berkefeld filtrates of broth cultures of certain strains of Staphylococcus aureus have a selective poisonous action for the skin of rabbits. 2. The poison is thermolabile, being completely destroyed when heated to 55 degrees C for 1 hour. 3. The poison when injected intradermally into rabbits stimulates the production of antitoxin. We therefore conclude that the poison is a soluble toxin.

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