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. 1925 Jul 31;42(2):123-42.
doi: 10.1084/jem.42.2.123.

ON THE ANTIGENS OF RED BLOOD CORPUSCLES : II. FLOCCULATION REACTIONS WITH ALCOHOLIC EXTRACTS OF ERYTHROCYTES

K Landsteiner  1 , J van der Scheer
Affiliations

ON THE ANTIGENS OF RED BLOOD CORPUSCLES : II. FLOCCULATION REACTIONS WITH ALCOHOLIC EXTRACTS OF ERYTHROCYTES

K Landsteiner et al. J Exp Med. .

Abstract

1. Flocculation reactions of anti-erythrocyte sera on emulsions of alcoholic extract of blood are described. 2. The reactions are markedly species-specific. 3. Besides the homologous reactions certain others-"heterogenetic"" ones-have been observed, and in this way the existence of new examples of heterogenetic antibodies has been demonstrated. 4. Group-specific substances can be extracted from human erythrocytes with alcohol and demonstrated by flocculation with group-specific immune sera. 5. A conception of the structure of cellular antigens based upon the known facts, is presented.

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References

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    1. J Exp Med. 1923 Jul 31;38(2):127-38 - PubMed
    1. J Exp Med. 1925 Feb 28;41(3):427-37 - PubMed