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. 1930 Apr 30;51(5):675-84.
doi: 10.1084/jem.51.5.675.

OBSERVATIONS ON THE PHAGOCYTOSIS OF THE PNEUMOCOCCUS BY HUMAN WHOLE BLOOD : I. THE NORMAL PHAGOCYTIC TITRE, AND THE ANTI-PHAGOCYTIC EFFECT OF THE SPECIFIC SOLUBLE SUBSTANCE

H K Ward  1
Affiliations

OBSERVATIONS ON THE PHAGOCYTOSIS OF THE PNEUMOCOCCUS BY HUMAN WHOLE BLOOD : I. THE NORMAL PHAGOCYTIC TITRE, AND THE ANTI-PHAGOCYTIC EFFECT OF THE SPECIFIC SOLUBLE SUBSTANCE

H K Ward. J Exp Med. .

Abstract

1. The phagocytic titre of whole human blood against the three types of pneumococcus was determined in a number of individuals. The titre varied over a considerable range in different subjects. 2. Contrary to expectation, the titre in early cases of untreated pneumonia was quite high against the infecting organism, pointing to a local rather than a general lowering of resistance in infection with this organism. 3. Sia's work was confirmed, that the specific carbohydrate has a specific anti-phagocytic action on the blood. This action is more marked in the case of Type III than in Type I.

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References

    1. J Exp Med. 1924 Jan 31;39(2):219-44 - PubMed
    1. J Exp Med. 1926 Apr 30;43(5):633-45 - PubMed