Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1930 Apr 30;51(5):729-41.
doi: 10.1084/jem.51.5.729.

EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS : THE EFFECT OF CROWDING UPON TUBERCULOSIS IN GUINEA PIGS, ACQUIRED BY CONTACT AND BY INOCULATION

M B Lurie  1
Affiliations

EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS : THE EFFECT OF CROWDING UPON TUBERCULOSIS IN GUINEA PIGS, ACQUIRED BY CONTACT AND BY INOCULATION

M B Lurie. J Exp Med. .

Abstract

1. If normal guinea pigs are confined with an equal number of tuberculous cage mates the incidence of "contact" tuberculosis is increased by crowding. This is probably due largely to an increase in the amount of tubercle bacilli available in the more crowded cages, although no constant relationship could be established between the intensity of the exposure and the incidence of tuberculosis acquired by contagion. Other factors must be determined. 2. If guinea pigs are inoculated intraperitoneally with a given quantity of human tubercle bacilli and distributed in different degrees of crowding, the duration of survival is shortened in the more crowded animals, and the incidence of chronic types of tuberculosis is greater among the less crowded animals.

PubMed Disclaimer

References

    1. J Exp Med. 1923 Jan 31;37(2):269-74 - PubMed
    1. J Exp Med. 1927 Jan 31;45(2):209-26 - PubMed
    1. J Exp Med. 1927 May 31;45(6):1025-35 - PubMed