Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1930 Jul 31;52(2):215-24.
doi: 10.1084/jem.52.2.215.

SUSCEPTIBILITY OF RABBITS TO INFECTION BY THE INHALATION OF TYPE II PNEUMOCOCCI

E G Stillman  1
Affiliations

SUSCEPTIBILITY OF RABBITS TO INFECTION BY THE INHALATION OF TYPE II PNEUMOCOCCI

E G Stillman. J Exp Med. .

Abstract

1. The susceptibility of rabbits to inhalations of pneumococci varies in direct proportion to the virulence of the organism for rabbits. 2. When rabbits are exposed to a pneumococcus spray, irrespective of the virulence of the organism, the bacteria readily penetrate into the lower respiratory tract. 3. When rabbits are exposed to a spray of avirulent degenerated "R" form of pneumococcus, septicemia does not occur and pneumococci are seldom recovered from the liver, kidney or spleen. 4. When rabbits are exposed to a spray of slightly virulent Pneumococcus Type II (SAv) a non-fatal septicemia may occur and pneumococci may be recovered from the liver, kidney and spleen. 5. When rabbits are exposed to a spray of virulent Type II (Sv) pneumococci, septicemia may occur which in certain instances terminates fatally. Pneumococci may also be recovered from the liver, kidney and spleen.

PubMed Disclaimer

References

    1. J Exp Med. 1922 Aug 31;36(3):317-28 - PubMed
    1. J Exp Med. 1923 Jul 31;38(2):117-26 - PubMed
    1. J Exp Med. 1926 Oct 31;44(5):581-7 - PubMed
    1. J Exp Med. 1927 May 31;45(6):1057-63 - PubMed