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. 1930 Sep 30;52(4):477-83.
doi: 10.1084/jem.52.4.477.

SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA

M Heidelberger  1 , R H Sia, F E Kendall
Affiliations

SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA

M Heidelberger et al. J Exp Med. .

Abstract

1. A rapid and simple method is given for the approximate determination of the specifically precipitable protein in Type I antipneumococcus sera. 2. It is shown that a close parallel exists between the specifically precipitable protein and the number of mouse protection units in a wide variety of Type I antipneumococcus sera. 3. Owing to the consistent results obtained and the rapidity, simplicity, and economy of the method, its use is proposed instead of the mouse protection test as a basis for the titration of standard sera and the comparison of others with a standard. 4. A method is given for conveniently preparing highly purified specific polysaccharide of Type I pneumococcus.

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References

    1. J Exp Med. 1915 Apr 1;21(4):389-400 - PubMed
    1. J Exp Med. 1925 Oct 31;42(5):727-45 - PubMed
    1. J Exp Med. 1929 Nov 30;50(6):809-23 - PubMed
    1. J Exp Med. 1930 Sep 30;52(4):471-6 - PubMed