Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1931 Sep 30;54(4):597-613.
doi: 10.1084/jem.54.4.597.

SERUM SICKNESS IN RABBITS : I. MANIFESTATIONS OF SERUM SICKNESS

M S Fleisher  1 , L Jones
Affiliations

SERUM SICKNESS IN RABBITS : I. MANIFESTATIONS OF SERUM SICKNESS

M S Fleisher et al. J Exp Med. .

Abstract

1. The injection of a single large dose of normal horse serum into rabbits results in the appearance 3 to 8 days later of erythematous and edematous reactions on the ears in 68.9 per cent of the animals. 2. The injections may be given by any of several routes and reactions appear when the site of injection is definitely distant from the ears. 3. Injections of various antisera into rabbits cause the appearance of similar reactions. 4. These reactions can be considered as manifestations of serum sickness in rabbits.

PubMed Disclaimer