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. 1932 Sep 30;56(4):575-85.
doi: 10.1084/jem.56.4.575.

STUDIES ON IMMUNITY TO SWINE INFLUENZA

R E Shope  1
Affiliations

STUDIES ON IMMUNITY TO SWINE INFLUENZA

R E Shope. J Exp Med. .

Abstract

Of the two etiological components of swine influenza, only the filtrable virus possessed immunizing properties. H. influenzae suis, while essential to the production of the disease, played only a secondary and contributory rôle and, alone, conferred no immunity. Serum of swine convalescent from the filtrate disease neutralized the swine influenza etiological complex of organism and virus. Intramuscularly administered swine influenza virus was incapable of inducing illness but did render hogs immune to swine influenza. It is suggested that a specific relationship, as regards infectivity, exists between the swine influenza virus and the tissues of the respiratory tract.

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References

    1. J Exp Med. 1921 Jan 1;33(1):69-75 - PubMed
    1. J Exp Med. 1931 Jul 31;54(3):373-85 - PubMed