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. 1933 Feb 28;57(3):373-9.
doi: 10.1084/jem.57.3.373.

STUDIES ON THE PRECIPITIN REACTION : PRECIPITATING HAPTENS; SPECIES DIFFERENCES IN ANTIBODIES

M Heidelberger  1 , F E Kendall
Affiliations

STUDIES ON THE PRECIPITIN REACTION : PRECIPITATING HAPTENS; SPECIES DIFFERENCES IN ANTIBODIES

M Heidelberger et al. J Exp Med. .

Abstract

1. Partial hydrolysis products of the specific polysaccharide of Type III pneumococcus ranging from 550 to 1,800 in formula weight can be quantitatively freed from unhydrolyzed polysaccharide. 2. The fractions yield specific precipitates with Type III antipneumococcus horse serum but fail to precipitate homologous rabbit antisera, giving rise only to specific inhibition. The aldobionic acid, the structural unit of S III, does not precipitate antisera. 3. A possible explanation and a possible application of the findings are pointed out.

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References

    1. J Exp Med. 1929 Nov 30;50(6):809-23 - PubMed
    1. J Exp Med. 1932 Mar 31;55(4):555-61 - PubMed
    1. J Exp Med. 1932 Aug 31;56(3):399-409 - PubMed