THE EFFECT OF HEMOGLOBIN INJECTIONS ON ERYTHROPOIESIS AND ERYTHROCYTE SIZE IN RABBITS RENDERED ANEMIC BY BLEEDING
- PMID: 19870250
- PMCID: PMC2132361
- DOI: 10.1084/jem.59.3.333
THE EFFECT OF HEMOGLOBIN INJECTIONS ON ERYTHROPOIESIS AND ERYTHROCYTE SIZE IN RABBITS RENDERED ANEMIC BY BLEEDING
Abstract
1. An anemia characterized by increased size of the red blood cells and a high color index was produced in rabbits by repeated bleeding and by the subcutaneous injection of stroma-free hemoglobin solution. 2. The bone marrow of these rabbits reverted to a more primitive stage than did the marrows of rabbits rendered anemic in the same manner but not treated with hemoglobin.
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