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. 1935 Apr 30;61(5):689-702.
doi: 10.1084/jem.61.5.689.

ENCEPHALOMYELITIS ACCOMPANIED BY MYELIN DESTRUCTION EXPERIMENTALLY PRODUCED IN MONKEYS

T M Rivers  1 , F F Schwentker
Affiliations

ENCEPHALOMYELITIS ACCOMPANIED BY MYELIN DESTRUCTION EXPERIMENTALLY PRODUCED IN MONKEYS

T M Rivers et al. J Exp Med. .

Abstract

The repeated intramuscular injections of aqueous emulsions and alcohol-ether extracts of sterile normal rabbit brains in some manner produced pathological changes accompanied by myelin destruction in the brains of 7 of 8 monkeys (Macacus rhesus). Eight, control monkeys remained well. Cultures from the involved brains remained sterile, and no transmissible agent was demonstrated by means of intracerebral inoculations of emulsions of bits of the brains into monkeys, rabbits, guinea pigs, and white mice.

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References

    1. J Exp Med. 1934 Oct 31;60(5):559-74 - PubMed
    1. Lancet. 1982 May 15;1(8281):1123 - PubMed