Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1936 Apr 30;63(5):745-65.
doi: 10.1084/jem.63.5.745.

ACTIVE IMMUNIZATION OF GUINEA PIGS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. IMMUNIZATION WITH FORMOLIZED VIRUS

H R Cox  1 , P K Olitsky
Affiliations

ACTIVE IMMUNIZATION OF GUINEA PIGS WITH THE VIRUS OF EQUINE ENCEPHALOMYELITIS : II. IMMUNIZATION WITH FORMOLIZED VIRUS

H R Cox et al. J Exp Med. .

Abstract

From a study by quantitative methods, the conclusion is reached that a resistance of high degree may be induced in guinea pigs and mice against experimental equine encephalomyelitis by means of formolized vaccines in which no active virus can be demonstrated. The induced resistance is not due to residual traces of active virus which might possibly have escaped detection in the formolized tissue preparations.

PubMed Disclaimer

References

    1. Science. 1934 Sep 14;80(2072):251-2 - PubMed
    1. Science. 1934 May 18;79(2055):459 - PubMed
    1. J Exp Med. 1935 Oct 31;62(5):677-85 - PubMed
    1. J Exp Med. 1935 Oct 31;62(5):687-95 - PubMed