Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1937 Jan 1;65(1):29-42.
doi: 10.1084/jem.65.1.29.

THE CAPILLARY SUPPLY IN NORMAL AND HYPERTROPHIED HEARTS OF RABBITS

R A Shipley  1 , L J Shipley, J T Wearn
Affiliations

THE CAPILLARY SUPPLY IN NORMAL AND HYPERTROPHIED HEARTS OF RABBITS

R A Shipley et al. J Exp Med. .

Abstract

1. During normal growth of the rabbit heart, muscle fibers enlarge, and the capillaries multiply so that a relatively constant capillary supply per unit of tissue is maintained from the time of birth to maturity. 2. In cardiac hypertrophy the muscle fibers enlarge, but the capillaries do not multiply and, as a result, the capillary supply per unit of tissue is reduced. 3. The decreased concentration of capillaries in the hypertrophied heart would constitute an impediment to the adequate exchange of metabolic substances, but the seriousness of the impediment cannot be estimated without further physiological data.

PubMed Disclaimer

References

    1. J Clin Invest. 1926 Dec;3(2):283-98 - PubMed
    1. J Exp Med. 1924 Aug 31;40(3):289-91 - PubMed
    1. J Exp Med. 1928 Jan 31;47(2):273-90 - PubMed
    1. Am J Pathol. 1925 Jul;1(4):351-372.1 - PubMed