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. 1991 Jan;59(1):453-6.
doi: 10.1128/iai.59.1.453-456.1991.

Median infective dose of Treponema pallidum determined in a highly susceptible guinea pig strain

K Wicher  1 , V Wicher
Affiliations

Median infective dose of Treponema pallidum determined in a highly susceptible guinea pig strain

K Wicher et al. Infect Immun. 1991 Jan.

Abstract

The median infective dose of Treponema pallidum subsp. pallidum and the production of immunity to reinfection in C4D guinea pigs have been determined with 10(1) to 10(6) organisms per infective dose. The mean infective dose is 10(2) organisms, and immunity--in those animals that demonstrated lesions--developed after 4.5 months postinfection.

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References

    1. Infect Immun. 1987 Oct;55(10):2502-8 - PubMed
    1. J Exp Med. 1971 Jul 1;134(1):162-75 - PubMed
    1. Crit Rev Microbiol. 1989;16(3):181-234 - PubMed
    1. Int Arch Allergy Appl Immunol. 1989;89(2-3):128-35 - PubMed
    1. Pathol Immunopathol Res. 1989;8(3-4):161-78 - PubMed

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