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. 1937 Mar 31;65(4):595-612.
doi: 10.1084/jem.65.4.595.

STUDIES ON THE SEROLOGICAL TYPING OF STREPTOCOCCUS HEMOLYTICUS

R H Pauli  1 , A F Coburn; Assistance of Florence Stone, Ph.D
Affiliations

STUDIES ON THE SEROLOGICAL TYPING OF STREPTOCOCCUS HEMOLYTICUS

R H Pauli et al. J Exp Med. .

Abstract

The cross-reactions which interfere with satisfactory serological identification of hemolytic streptococcus are due to anticarbohydrate in the sera used for typing. This antibody can be removed easily by absorption with purified streptococcus carbohydrate, and type identification is then readily established. The serological classification of hemolytic streptococcus from throat infections contracted in New York during 1935 and 1936 showed the predominance of types 4, 13 and 22. Type 13 appeared to be the most serious in initiating rheumatic activity during this period of observation.

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References

    1. J Clin Invest. 1935 Nov;14(6):755-62 - PubMed
    1. J Exp Med. 1919 Sep 1;30(3):179-213 - PubMed
    1. J Exp Med. 1932 Oct 31;56(5):633-50 - PubMed