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. 1938 Oct 31;68(6):837-52.
doi: 10.1084/jem.68.6.837.

CELLULAR REACTIONS TO TUBERCULO-PROTEINS COMPARED WITH THE REACTIONS TO TUBERCULO-LIPIDS

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CELLULAR REACTIONS TO TUBERCULO-PROTEINS COMPARED WITH THE REACTIONS TO TUBERCULO-LIPIDS

F R Sabin. J Exp Med. .

Abstract

1. Tuberculo-protein in solution induces the formation of monocytes in the normal animal and tubercles of epithelioid cells in that which is tuberculous. 2. Freshly precipitated tuberculo-proteins from the culture media and from the bacilli induce a moderate formation of epithelioid cells in normal animals, and more in the tuberculous. 3. Insoluble forms of tuberculo-protein induce complex tubercular tissue in normal animals. This action is enhanced in the tuberculous.

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References

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