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. 1939 Jul 31;70(2):141-6.
doi: 10.1084/jem.70.2.141.

PRODUCTION IN MONKEYS OF COMPLEMENT-FIXING ANTIBODIES WITHOUT ACTIVE IMMUNITY BY INJECTION OF KILLED PLASMODIUM KNOWLESI

M D Eaton  1 , L T Coggeshall
Affiliations

PRODUCTION IN MONKEYS OF COMPLEMENT-FIXING ANTIBODIES WITHOUT ACTIVE IMMUNITY BY INJECTION OF KILLED PLASMODIUM KNOWLESI

M D Eaton et al. J Exp Med. .

Abstract

Injection into rhesus monkeys of Plasmodium knowlesi killed by heat, formalin, drying, or freezing and thawing stimulates the production of complement-fixing antibodies, but no demonstrable agglutinating or protective antibodies are formed. Possible differences in the immunity mechanisms concerned in active infection and in artificial immunization are discussed.

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References

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