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. 1943 Feb 1;77(2):97-110.
doi: 10.1084/jem.77.2.97.

AN IMMUNOLOGICAL AND ELECTROPHORETIC COMPARISON OF THE ANTIBODY TO C POLYSACCHARIDE AND THE C-REACTIVE PROTEIN OF ACUTE PHASE SERUM

E Perlman  1 , J G Bullowa, R Goodkind
Affiliations

AN IMMUNOLOGICAL AND ELECTROPHORETIC COMPARISON OF THE ANTIBODY TO C POLYSACCHARIDE AND THE C-REACTIVE PROTEIN OF ACUTE PHASE SERUM

E Perlman et al. J Exp Med. .

Abstract

1. Studies of the precipitation reaction of C polysaccharide with C protein, and of C polysaccharide with C antibody are reported. The similarity between these two systems in this respect is demonstrated. 2. The differences between C protein and C antibody are emphasized. The differences between this protein and antibodies in general have been reported previously by others. 3. Electrophoretic studies show that C antibody is in the gamma globulin fraction of serum whereas C protein migrates with the alpha(1) globulin fraction of acute phase protein.

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