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. 1944 Jan 1;79(1):79-88.
doi: 10.1084/jem.79.1.79.

STUDIES ON THE ANTIGENIC COMPOSITION OF GROUP A HEMOLYTIC STREPTOCOCCI : II. THE OCCURRENCE OF STRAINS IN A GIVEN TYPE CONTAINING M BUT NO T ANTIGEN

R C Lancefield  1 , W A Stewart
Affiliations

STUDIES ON THE ANTIGENIC COMPOSITION OF GROUP A HEMOLYTIC STREPTOCOCCI : II. THE OCCURRENCE OF STRAINS IN A GIVEN TYPE CONTAINING M BUT NO T ANTIGEN

R C Lancefield et al. J Exp Med. .

Abstract

1. Group A hemolytic streptococci have been described which do not agglutinate in anti-T serum because they lack T antigen. 2. Other strains occur which contain T antigen yet do not agglutinate in anti-T serum because T agglutination is blocked by the presence of large amounts of M substance in the streptococci. 3. Strains belonging to a number of types have been analyzed to determine their antigenic composition with respect to M and T antigens.

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References

    1. J Exp Med. 1940 Mar 31;71(4):521-37 - PubMed
    1. J Exp Med. 1943 Dec 1;78(6):465-76 - PubMed