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. 1946 Mar 31;83(4):321-8.

MOUSE-PROTECTIVE TITERS OF SERA OF VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES

A W Walter  1 , E L Schenkein, W D Sutliff
Affiliations

MOUSE-PROTECTIVE TITERS OF SERA OF VOLUNTEERS FOLLOWING INJECTION OF PNEUMOCOCCI OR THEIR TYPE-SPECIFIC POLYSACCHARIDES

A W Walter et al. J Exp Med. .

Abstract

1. Sera of human subjects immunized with pneumococci or their type-specific polysaccharides showed type-specific antibody by mouse protection tests as well as on determinations of the specifically precipitable nitrogen. 2. The ratio, mouse-protective units to antibody nitrogen, was less in human sera of low potency than in more potent human or animal sera.

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References

    1. Am J Public Health Nations Health. 1940 Apr;30(4):361-8 - PubMed
    1. J Exp Med. 1946 Mar 31;83(4):303-20 - PubMed
    1. J Exp Med. 1932 May 31;55(6):853-65 - PubMed
    1. J Exp Med. 1930 Sep 30;52(4):573-85 - PubMed
    1. J Exp Med. 1937 Sep 30;66(4):413-24 - PubMed

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