VITAMIN A IN EYE TISSUES
- PMID: 19872899
- PMCID: PMC2141403
- DOI: 10.1085/jgp.18.6.905
VITAMIN A IN EYE TISSUES
Abstract
1. Vitamin A has been found in the retinas and the combined pigment epithelia and choroid layers of frogs, pigs, sheep, and cattle. The vitamin was identified by (a) its specific absorption at 328 mmicro; (b) the blue color yielded with antimony trichloride, associated with an absorption band at about 620 mmicro; (c) anti-xerophthalmic and growth-promoting activity; and (d) quantitative relationships among the results of these three types of observation. 2. The mammalian retinas contain about 22gamma, the frog retinas about 400gamma, and the frog pigmented layers almost 2 mg. of vitamin A per gram of dry tissue. 3. With the possible exception of hepaxanthin, no other carotenoids were found in the mammalian tissues.
Similar articles
-
THE PORPHYROPSIN VISUAL SYSTEM.J Gen Physiol. 1939 Jul 20;22(6):775-94. doi: 10.1085/jgp.22.6.775. J Gen Physiol. 1939. PMID: 19873132 Free PMC article.
-
Iodopsin.J Gen Physiol. 1955 May 20;38(5):623-81. doi: 10.1085/jgp.38.5.623. J Gen Physiol. 1955. PMID: 14367777 Free PMC article.
-
CAROTENOIDS AND THE VISUAL CYCLE.J Gen Physiol. 1935 Nov 20;19(2):351-71. doi: 10.1085/jgp.19.2.351. J Gen Physiol. 1935. PMID: 19872932 Free PMC article.
-
Nutritargeting.Adv Food Nutr Res. 2008;54:179-217. doi: 10.1016/S1043-4526(07)00005-8. Adv Food Nutr Res. 2008. PMID: 18291307 Review.
-
Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease.Prog Retin Eye Res. 2001 Mar;20(2):175-208. doi: 10.1016/s1350-9462(00)00027-6. Prog Retin Eye Res. 2001. PMID: 11173251 Review.
Cited by
-
Oligomerization of G protein-coupled receptors: past, present, and future.Biochemistry. 2004 Dec 21;43(50):15643-56. doi: 10.1021/bi047907k. Biochemistry. 2004. PMID: 15595821 Free PMC article. Review.
-
Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody.FASEB J. 2020 Oct;34(10):13918-13934. doi: 10.1096/fj.202000796RR. Epub 2020 Aug 28. FASEB J. 2020. PMID: 32860273 Free PMC article.
-
Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X.Nutr Metab (Lond). 2023 Aug 15;20(1):34. doi: 10.1186/s12986-023-00750-3. Nutr Metab (Lond). 2023. PMID: 37582723 Free PMC article. Review.
-
Bilateral microbial keratitis in a case of severe xerophthalmia following small bowel resection.J R Soc Med. 2011 Mar;104(3):124-6. doi: 10.1258/jrsm.2010.100326. J R Soc Med. 2011. PMID: 21357982 Free PMC article. No abstract available.
-
Vitamin A (retinoid) metabolism and actions: What we know and what we need to know about amphibians.Zoo Biol. 2014 Nov-Dec;33(6):527-35. doi: 10.1002/zoo.21140. Epub 2014 Jun 24. Zoo Biol. 2014. PMID: 24958673 Free PMC article. Review.