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Review
. 2009 Jul;49(7):848-52.

[Type III secretion system of Vibrio parahaemolyticus--a review]

[Article in Chinese]
Affiliations
  • PMID: 19873746
Review

[Type III secretion system of Vibrio parahaemolyticus--a review]

[Article in Chinese]
Ying Yu et al. Wei Sheng Wu Xue Bao. 2009 Jul.

Abstract

Vibrio parahaemolyticus is a halophilic gram-negative bacterium that causes food borne acute gastroenteritis in human being or certain diseases in aquatic species. In addition to thermostable direct hemolysin (tdh) and tdh-related hemolysin (trh), two sets of type III secretion systems (T3SS) were recently found to be associated closely with virulence. T3SS1 located on chromosome 1 is involved in cytotoxicity to host cells and orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and eventual cell lysis. T3SS2 in chromosome 2 is enterotoxic. In this we address the composition of the two T3SS, their functions and regulation in Vibrio parahaemolyticus.

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