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Review
. 2009 Nov;32 Suppl 2(Suppl 2):S253-9.
doi: 10.2337/dc09-S318.

Insulin therapy for type 2 diabetes

Sanne G Swinnen  1 , Joost B Hoekstra, J Hans DeVries
Affiliations
Review

Insulin therapy for type 2 diabetes

Sanne G Swinnen et al. Diabetes Care. 2009 Nov.
No abstract available

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Figures

Figure 1
Figure 1
Relationships between mean end point daily insulin dose (A) and the frequency of patient contact (clinical visits and telephone contacts combined) (B) and mean reduction in A1C, and between mean end point daily insulin dose and mean weight gain (C), during nine randomized trials investigating insulin initiation with NPH insulin, insulin detemir, or insulin glargine. Included studies are Bretzel et al. (34), Fritsche et al. (35), Hermansen et al. (28), Holman et al. (32), Philis-Tsimikas et al. (33), Riddle et al. (27), Rosenstock et al. (29), Yki-Järvinen et al. (36), and Yki-Järvinen et al. (37) (A and C). B does not include Holman, since this publication did not specify the number of interim telephone contacts. Two trials (28,35) did not report mean end point daily insulin dose as units per kilogram per day. We calculated the desired figures from the mean end point dose reported as units per day and mean body weight at study end. Three studies (Riddle and the two studies of Yki-Järvinen [27,36,37]) did not report reduction in A1C. We calculated these values from mean baseline and end point A1C levels.
See this image and copyright information in PMC

References

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