Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Oct;5(10):e1000543.
doi: 10.1371/journal.pcbi.1000543. Epub 2009 Oct 30.

Getting started in gene expression microarray analysis

Donna K Slonim  1 , Itai Yanai
Affiliations
Review

Getting started in gene expression microarray analysis

Donna K Slonim et al. PLoS Comput Biol. 2009 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Overview of steps in a typical gene expression microarray experiment.
Topics in blue boxes with solid borders are addressed in the Experimental Design section, those in green boxes with dashed borders are covered in the section on data preparation, and those in purple boxes with dash-dotted borders are discussed in the Data Analysis section of this review.
See this image and copyright information in PMC

References

    1. Kerr MK, Churchill GA. Experimental design for gene expression microarrays. Biostatistics. 2001;2:183–201. - PubMed
    1. Yang YH, Speed T. Design issues for cDNA microarray experiments. Nat Rev Genet. 2002;3:579–588. - PubMed
    1. Irizarry RA, Warren D, Spencer F, Kim IF, Biswal S, et al. Multiple-laboratory comparison of microarray platforms. Nat Methods. 2005;2:345–350. - PubMed
    1. Shi L, Reid LH, Jones WD, Shippy R, Warrington JA, et al. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol. 2006;24:1151–1161. - PMC - PubMed
    1. Altman NS, Hua J. Extending the loop design for two-channel microarray experiments. Genet Res. 2006;88:153–163. - PubMed

Publication types

MeSH terms