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. 2009 Oct 30;139(3):456-7.
doi: 10.1016/j.cell.2009.10.011.

Tetherin is as tetherin does

Jason Hammonds  1 , Paul Spearman
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Free article
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Tetherin is as tetherin does

Jason Hammonds et al. Cell. .
Free article

Abstract

Tetherin is a cellular restriction factor that inhibits the release of HIV and other enveloped viruses from host cells. A paper from Perez-Caballero et al. (2009) in this issue of Cell clarifies how this factor works. The authors show that the aptly named tetherin directly tethers viral particles to the plasma membrane.

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