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Review
. 2010 Jan;87(1):107-16.
doi: 10.1189/jlb.0809566. Epub 2009 Oct 30.

CD57+ T lymphocytes and functional immune deficiency

Daniele Focosi  1 , Marco Bestagno, Oscar Burrone, Mario Petrini
Affiliations
Review

CD57+ T lymphocytes and functional immune deficiency

Daniele Focosi et al. J Leukoc Biol. 2010 Jan.

Abstract

CD57(+) expression in T lymphocytes has been recognized for decades as a marker of in vitro replicative senescence. In recent years, accumulating evidences have pointed on the utility of this marker to measure functional immune deficiency in patients with autoimmune disease, infectious diseases, and cancers. We review here the relevant literature and implications in clinical settings.

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