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Case Reports
. 2009 Jan-Mar;13(1):41-3.
doi: 10.4103/0972-5229.53117.

Severe myocardial depression in a patient with aluminium phosphide poisoning: a clinical, electrocardiographical and histopathological correlation

Viral Shah  1 , Seema Baxi, Tanmay Vyas
Affiliations
Case Reports

Severe myocardial depression in a patient with aluminium phosphide poisoning: a clinical, electrocardiographical and histopathological correlation

Viral Shah et al. Indian J Crit Care Med. 2009 Jan-Mar.

Abstract

Aluminium phosphide poisoning is very common in India. It is one of the most fatal poisons. The clinical spectrum of poisoning varies depending upon the dosage and duration of consumption. The main effect of the poison is due to the release of phosphine which inhibits cytochrome oxidase and thereby hampers cellular oxygen utilization. Almost any organ can be affected by aluminium phosphide poisoning. We report a case where the heart was the predominantly affected organ. We describe the clinical symptoms and signs and their correlation with electrocardiographic and histopathological examinations.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Showing ST elevation in inferior oriented leads mimicking inferior wall myocardial infraction
Figure 2
Figure 2
Showing ST elevation with broad QRS complex mimicking anterior wall myocardial infarction with bundle branch block
Figure 3
Figure 3
Severe degree of vacuolation in myocytes. (H and E, ×40)
Figure 4
Figure 4
Necrosis and myocytolysis in many of the myocardial fibers. (H and E, ×40)
See this image and copyright information in PMC

References

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