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. 2008;53(3):146-8.
doi: 10.4103/0019-5154.43207.

Metastatic Crohn's disease of external genitalia

Charles Panackel  1 , Joseph John, Devadas Krishnadas, Kattoor R Vinayakumar
Affiliations

Metastatic Crohn's disease of external genitalia

Charles Panackel et al. Indian J Dermatol. 2008.

Abstract

Metastatic Crohn's disease is an uncommon extraintestinal manifestation of Crohn's disease. Its hallmark features include the presence of cutaneous noncaseating granulomas that are noncontiguous with the gastrointestinal tract or fistula. We report a rare case of metastatic Crohn's disease involving the external genitalia in a 14-year-old girl. Diagnosis was based on skin biopsy. Patient had complete recovery on treatment with oral and topical steroids along with azathioprine.

Keywords: Extraintestinal manifestation of IBD; metastatic Crohn's disease; noncaseating granuloma.

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Fig. 1
Fig. 1
Multiple papules, nodules and ulcers on the external genitalia and surrounding skin
Fig. 2
Fig. 2
Skin biopsy showing noncaseating granuloma (H&E, ×100)
Fig. 3
Fig. 3
Skin biosy showing multinucleate giant cell and epitheloid cells (H&E, ×400)
See this image and copyright information in PMC

References

    1. Goyal A, Mansel RE, Young HL, Douglas-Jones A. Metastatic cutaneous Crohn's disease of the nipple: Report of a case. Dis Colon Rectum. 2006;49:132–4. - PubMed
    1. Burgdorf W. Cutaneous manifestations of Crohn's disease. J Am Acad Dermatol. 1981;5:689–95. - PubMed
    1. Parks AG, Morson BC, Pegum JS. Crohn's disease with cutaneous involvement. Proc R Soc Med. 1965;58:241–2. - PMC - PubMed
    1. Mountain JC. Cutaneous ulceration in Crohn's disease. Gut. 1970;11:18–26. - PMC - PubMed
    1. Guest GD, Fink RL. Metastatic Crohn's disease: Case report of an unusual variant and review of the literature. Dis Colon Rectum. 2000;43:1764–6. - PubMed