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. 2009 Oct;42 Suppl(Suppl):S51-5.
doi: 10.4103/0970-0358.57187.

Syndromes and anomalies associated with cleft

Affiliations

Syndromes and anomalies associated with cleft

R Venkatesh. Indian J Plast Surg. 2009 Oct.

Abstract

Orofacial clefts are one of the commonest birth defects, and may be associated with other congenital anomalies. The majority of these orofacial clefts are nonsyndromic . A significant percentage of these clefts both syndromic and non-syndromic may have associated anomalies. Apart from reviewing other studies, this article also analyses a study of associated anomalies from a tertiary cleft centre in India.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Van der Woude syndrome with lower lip pits
Figure 2
Figure 2
Pierre Robin sequence
Figure 3
Figure 3
Velocardiofacial syndrome with typical facies
Figure 4
Figure 4
Median facial dysplasia

References

    1. Leth Jensen B, Kreiborg S, Dahl E, Fogh-Andersen P. Cleft lip and palate in Denmark, 1976-1981: epidemiology, variability, and early somatic development. Cleft Palate. 1988;25:258–69. - PubMed
    1. Shprintzen RJ, Sigel-Sadewitz VL, Amato J, Goldberg RB. Anomalies associated with clefts lip, cleft palate, or both. Am J Med Gent. 1985;20:585–95. - PubMed
    1. Cohen MM., Jr Syndromes with Cleft lip and cleft palate. Cleft Palate J. 1978;15:306–28. - PubMed
    1. Winter RM, Baraister M. London dysmorpholgy Database, London neurogenetics database and Dysmorphology photo library on CD-ROM (version 3) Oxford: Oxford University press; 2001.
    1. Berge SJ, Plath H, Van de Vondel PT, Appel T, Niederhagen B, Von Lindern JJ, et al. Fetal cleft lip and palate: sonographic diagnosis, chromosomal abnormalities, associated anomalies and postnatal outcome in 70 fetuses. Ultrasound Obstet Gynecol. 2001;18:422–31. - PubMed