Review
doi: 10.1016/j.ccc.2009.08.002.
The pathophysiology of septic shock
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- PMID: 19892247
- DOI: 10.1016/j.ccc.2009.08.002
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Review
The pathophysiology of septic shock
Crit Care Clin.
2009 Oct.
Abstract
There is a profound cellular dysfunction in sepsis, that clinically manifests as a continuum from simple, uncomplicated sepsis to severe sepsis, and finally to septic shock. Septic shock remains a significant challenge for clinicians. Recent advances in cellular and molecular biology have significantly improved our understanding of its pathogenetic mechanisms. These improvements will translate to better care and improved outcomes for these patients.
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