Editorial
doi: 10.1186/ar2837.
Epub 2009 Nov 5.
SAPHO syndrome: is a range of pathogen-associated rheumatic diseases extended?
- PMID: 19895718
- PMCID: PMC3003498
- DOI: 10.1186/ar2837
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Editorial
SAPHO syndrome: is a range of pathogen-associated rheumatic diseases extended?
Arthritis Res Ther.
2009.
Abstract
SAPHO syndrome, representing a constellation of synovitis, acne, palmo-plantar pustulosis, hyperostosis, and osteitis, is now recognized as a distinct medical entity: a reactive infectious osteitis. Genetic, immunological, and bacterial mechanisms are implicated in the development of the disease. Diagnostic problems may arise due to non-complete manifestations of SAPHO: either acne and arthritis or acne and anterior wall osteitis with an unclear pustulosis history. The interventional study of Assmann et al. is a significant addition to a long range of publications showing an association of SAPHO with Propionibacterium acnes. Randomized control studies are needed to confirm the effects of antibiotic therapy.
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References
-
- Amital H, Govoni M, Maya R, Meroni PL, Ori B, Shoenfeld Y, Tincani A, Trotta F, Sarzi-Puttini P, Atzeni F. Role of infectious agents in systemic rheumatic diseases. Clin Exp Rheumatol. 2008;26(1 Suppl 48):S27–32. - PubMed
-
- Arnson Y, Rubibow A, Amital H. Secondary syphilis presenting as SAPHO syndrome features. Clin Exp Rheumatol. 2008;26:1119–1121. - PubMed
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