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Comment
. 2009 Nov 6;5(5):451-2.
doi: 10.1016/j.stem.2009.10.011.

Preview. The Tortoise, the hare, and the FoxO

Edmund Chen  1 , Toren Finkel
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Free article
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Preview. The Tortoise, the hare, and the FoxO

Edmund Chen et al. Cell Stem Cell. .
Free article

Abstract

Maintaining stem cell quiescence is intimately connected to preserving long-term self-renewal potential. In this issue of Cell Stem Cell,Paik et al. (2009) and Renault et al. (2009) demonstrate a role for FoxO transcription factors in regulating neural stem cell proliferation and in maintaining stem and progenitor cell homeostasis.

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  • FoxO3 regulates neural stem cell homeostasis.
    Renault VM, Rafalski VA, Morgan AA, Salih DA, Brett JO, Webb AE, Villeda SA, Thekkat PU, Guillerey C, Denko NC, Palmer TD, Butte AJ, Brunet A. Renault VM, et al. Cell Stem Cell. 2009 Nov 6;5(5):527-39. doi: 10.1016/j.stem.2009.09.014. Cell Stem Cell. 2009. PMID: 19896443 Free PMC article.
  • FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.
    Paik JH, Ding Z, Narurkar R, Ramkissoon S, Muller F, Kamoun WS, Chae SS, Zheng H, Ying H, Mahoney J, Hiller D, Jiang S, Protopopov A, Wong WH, Chin L, Ligon KL, DePinho RA. Paik JH, et al. Cell Stem Cell. 2009 Nov 6;5(5):540-53. doi: 10.1016/j.stem.2009.09.013. Cell Stem Cell. 2009. PMID: 19896444 Free PMC article.

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