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. 2010 Feb;20(2):143-6.

doi: 10.1097/FPC.0b013e3283339bf3.

PharmGKB summary: very important pharmacogene information for angiotensin-converting enzyme

Caroline F Thorn¹, Teri E Klein, Russ B Altman

Affiliations

PMID: 19898265
PMCID: PMC3098760
DOI: 10.1097/FPC.0b013e3283339bf3

PharmGKB summary: very important pharmacogene information for angiotensin-converting enzyme

Caroline F Thorn et al. Pharmacogenet Genomics. 2010 Feb.

. 2010 Feb;20(2):143-6.

doi: 10.1097/FPC.0b013e3283339bf3.

Authors

Caroline F Thorn¹, Teri E Klein, Russ B Altman

Affiliation

¹ Department of Genetics, Stanford University Medical Center, Stanford, CA 94305-5120, USA.

PMID: 19898265
PMCID: PMC3098760
DOI: 10.1097/FPC.0b013e3283339bf3

No abstract available

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References

1. Turner AJ, Hooper NM. The angiotensin-converting enzyme gene family: genomics and pharmacology. Trends Pharmacol Sci. 2002;23:177–183. - PubMed
1. Tom B, Dendorfer A, Danser AH. Bradykinin, angiotensin-(1–7), and ACE inhibitors: how do they interact? Int J Biochem Cell Biol. 2003;35:792–801. - PubMed
1. Castellon R, Hamdi HK. Demystifying the ACE polymorphism: from genetics to biology. Curr Pharm Des. 2007;13:1191–1198. - PubMed
1. Oba R, Igarashi A, Kamata M, Nagata K, Takano S, Nakagawa H. The N-terminal active centre of human angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide. Eur J Neurosci. 2005;21:733–740. - PubMed
1. Sayed-Tabatabaei FA, Oostra BA, Isaacs A, van Duijn CM, Witteman JC. ACE polymorphisms. Circ Res. 2006;98:1123–1133. - PubMed

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