Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2009 Nov;4(11):710-1.
doi: 10.1038/nnano.2009.326.

Bioimaging: second window for in vivo imaging

Affiliations
Comment

Bioimaging: second window for in vivo imaging

Andrew M Smith et al. Nat Nanotechnol. 2009 Nov.

Abstract

Enhanced fluorescence from carbon nanotubes and advances in near-infrared cameras have opened up a new wavelength window for small animal imaging.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Optical windows in biological tissues
Top: These plots of effective attenuation coefficient (on a log scale) versus wavelength show that absorption and scattering from oxygenated blood, deoxygenated blood, skin and fatty tissue is lowest in either the first (pink shaded area) or second (grey) near-infrared window,. Bottom: Sensitivity curves for typical cameras based on silicon (Si), indium gallium arsenide (InGaAs) or mercury cadmium telluride (HgCdTe) sensors. Si and InGaAs cameras are sensitive within the first and second near-infrared windows, respectively, whereas HgCdTe is most sensitive at longer wavelengths.

Comment on

References

    1. Weissleder R. Nature Biotechnol. 2001;19:316–317. - PubMed
    1. Frangioni JV. Curr Opin Chem Biol. 2003;7:626–634. - PubMed
    1. Gao XH, Cui YY, Levenson RM, Chung LWK, Nie SM. Nature Biotechnol. 2004;22:969–976. - PubMed
    1. Lim YT, et al. Mol Imaging. 2003;2:50–64. - PubMed
    1. Welsher K, et al. Nature Nanotech. 2009;4:773–780. - PMC - PubMed