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Review
. 2010 Mar;32(3):331-9.
doi: 10.1007/s10529-009-0163-6. Epub 2009 Nov 8.

Recovery of succinic acid from fermentation broth

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Review

Recovery of succinic acid from fermentation broth

Tanja Kurzrock et al. Biotechnol Lett. 2010 Mar.

Abstract

Succinic acid is of high interest as bio-feedstock for the chemical industry. It is a precursor for a variety of many other chemicals, e.g. 1,4-butandiol, tetrahydrofuran, biodegradable polymers and fumaric acid. Besides optimized production strains and fermentation processes it is indispensable to develop cost-saving and energy-effective downstream processes to compete with the current petrochemical production process. Various methods such as precipitation, sorption and ion exchange, electrodialysis, and liquid-liquid extraction have been investigated for the recovery of succinic acid from fermentation broth and are reviewed critically here.

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