The portals of entry of herpes simplex virus infections
- PMID: 198999
Item in Clipboard
The portals of entry of herpes simplex virus infections
Zentralbl Bakteriol Orig A.
1977 Jul.
Abstract
In the present paper different possible portals of entry into the body for Herpes simplex Virus are examined. The possibility to infect the cornea with HsV without a preceding scarification was established. Scanning microscopy clearly showed the lesions of the infected cornea and a parallelity between the concentration of the inoculum and the spread of lesions. The i.c., i.m. and i.p. portals of entry are compared as to their capacity to produce encephalitis. The titration of virus may also be realized in the animal experiment. The intragastric portal of entry could be clearly demonstrated. So it is possible to explain herpes encephalitis in human newborns from mothers infected with Herpes virus.
Similar articles
-
Characterization of encephalitis in adult mice induced by intracerebral inoculation of herpes simplex virus type 1 (KOS) and comparison with mutants showing decreased virulence.Lab Invest. 1989 Jun;60(6):822-30. Lab Invest. 1989. PMID: 2543866
-
Comparative studies on some herpes simplex virus strains with different locations. II. Study of the virulence character.Rev Roum Virol (1972). 1973;10(1):39-46. Rev Roum Virol (1972). 1973. PMID: 4350923 No abstract available.
-
Histopathological examination of the cornea in experimental herpes simplex keratitis.Bull Ophthalmol Soc Egypt. 1976;69(73):127-33. Bull Ophthalmol Soc Egypt. 1976. PMID: 199300 No abstract available.
-
Herpes simplex virus ocular infections: current concepts of acute, latent and reactivated disease.Trans Am Ophthalmol Soc. 1990;88:727-96. Trans Am Ophthalmol Soc. 1990. PMID: 1965619 Free PMC article. Review. No abstract available.
-
Pathogenesis and latency of herpes simplex virus type 1 (HSV-1): an ophthalmologist's view of the eye as a model for the study of the virus-host relationship.Adv Exp Med Biol. 1990;278:205-9. doi: 10.1007/978-1-4684-5853-4_21. Adv Exp Med Biol. 1990. PMID: 1963036 Review. No abstract available.