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. 2008 Apr;28(2):38-44.
doi: 10.4103/0973-3930.43097.

The effect of periodontal therapy on the improvement of glycemic control in patients with type 2 diabetes mellitus: A randomized controlled clinical trial

Affiliations

The effect of periodontal therapy on the improvement of glycemic control in patients with type 2 diabetes mellitus: A randomized controlled clinical trial

Sukhdeep Singh et al. Int J Diabetes Dev Ctries. 2008 Apr.

Abstract

Aims: The purpose of this study is to investigate the effect of improved periodontal health on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have generalized periodontitis.

Materials and methods: A total of 45 type 2 DM patients with generalized periodontitis were selected for the study. The selected patients were randomly assigned to three groups (groups A, B, and C) comprising 15 patients each: * Group A received treatment with scaling and root planing only. * Group B received treatment with scaling and root planing followed by systemic doxycycline. * Group C received no treatment (control group). The periodontal parameters recorded included plaque index, gingival index, probing pocket depth, and clinical attachment level. These parameters were recorded at baseline (day zero), at 1 month, and at the end of 3 months. The following metabolic parameters were recorded: fasting blood glucose (FBG), postprandial blood glucose (PPBG), and glycated hemoglobin. These were recorded at baseline (day zero) and at the end of 3 months.

Statistical analysis: All the parameters were subjected to repeated-measures ANOVA and Scheffe's post hoc test.

Results: A statistically significant effect could be demonstrated for periodontal parameters for both group A and group B (treatment groups). Glycated hemoglobin values showed statistically significant decrease in treatment groups compared to the control group, with group B showing more significant decrease than group A.

Conclusions: The results of this study showed that nonsurgical periodontal treatment is associated with improved glycemic control in type 2 DM patients.

Keywords: Glycemic control; glycated hemoglobin; periodontal treatment; type 2 diabetes mellitus.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Measurement of the periodontal parameters using occlusal stent.
Figure 2
Figure 2
Periodontal condition of a type 2 DM patient with uncontrolled diabetes.
Figure 3
Figure 3
Same patient 3 months after extraction of hopeless teeth and periodontal treatment.

References

    1. Kiran M, Arpak N, Unsal E, Erdogan MF. The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. J Clin Periodontol. 2005;32:266–72. - PubMed
    1. Wassel RR, Preshaw PM. Type 2 diabetes mellitus as a risk factor for periodontal disease. Periodontology. 2006;3:243–52.
    1. Shlossman M, Knowler WC, Pettit DJ, Genco RJ. Type 2 diabetes mellitus and periodontal disease. J Am Dent Assoc. 1990;121:532–36. - PubMed
    1. Taylor GW, Burt BA, Becker MP, Shlossman M. Severe periodontitis and risk for poor glycemic control in patients with non-insulin dependant diabetes mellitus. J Periodontol. 1996;67:1085–93. - PubMed
    1. Loe H. Periodontal disease the sixth complication of diabetes mellitus. Diabetes care. 1993;16:324–34. - PubMed

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