The effect of periodontal therapy on the improvement of glycemic control in patients with type 2 diabetes mellitus: A randomized controlled clinical trial
- PMID: 19902046
- PMCID: PMC2772010
- DOI: 10.4103/0973-3930.43097
The effect of periodontal therapy on the improvement of glycemic control in patients with type 2 diabetes mellitus: A randomized controlled clinical trial
Abstract
Aims: The purpose of this study is to investigate the effect of improved periodontal health on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have generalized periodontitis.
Materials and methods: A total of 45 type 2 DM patients with generalized periodontitis were selected for the study. The selected patients were randomly assigned to three groups (groups A, B, and C) comprising 15 patients each: * Group A received treatment with scaling and root planing only. * Group B received treatment with scaling and root planing followed by systemic doxycycline. * Group C received no treatment (control group). The periodontal parameters recorded included plaque index, gingival index, probing pocket depth, and clinical attachment level. These parameters were recorded at baseline (day zero), at 1 month, and at the end of 3 months. The following metabolic parameters were recorded: fasting blood glucose (FBG), postprandial blood glucose (PPBG), and glycated hemoglobin. These were recorded at baseline (day zero) and at the end of 3 months.
Statistical analysis: All the parameters were subjected to repeated-measures ANOVA and Scheffe's post hoc test.
Results: A statistically significant effect could be demonstrated for periodontal parameters for both group A and group B (treatment groups). Glycated hemoglobin values showed statistically significant decrease in treatment groups compared to the control group, with group B showing more significant decrease than group A.
Conclusions: The results of this study showed that nonsurgical periodontal treatment is associated with improved glycemic control in type 2 DM patients.
Keywords: Glycemic control; glycated hemoglobin; periodontal treatment; type 2 diabetes mellitus.
Conflict of interest statement
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