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Review
. 2009 Dec;11(6):442-7.
doi: 10.1007/s11894-009-0068-5.

Gut sensing mechanisms

Arushi deFonseka  1 , Jonathan Kaunitz
Affiliations
Review

Gut sensing mechanisms

Arushi deFonseka et al. Curr Gastroenterol Rep. 2009 Dec.

Abstract

The mechanisms by which the gut senses and responds to nutrients involve the interplay of multiple complex pathways. In addition to regulating digestion and absorption, the pathways stimulated by molecules in the gut lumen mediate gastric motility, food intake, and satiety. Furthermore, protective mechanisms are activated as necessary to prevent injury, promote healing, and limit intake and absorption of potentially toxic substances. This review provides an update on the current knowledge and recent findings related to gastric sensing of nutrients, highlighting recent research and future endeavors in the field.

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