Chapter 13 - Soft hybrid nanostructures composed of phospholipid liposomes decorated with oligonucleotides

Abstract

This chapter reports on the design, preparation, and characterization of liposomes decorated with synthetic lipid-oligonucleotide conjugates. Several key parameters should be considered for a successful preparation of these functional nanostructures that can be employed further as building blocks in DNA-directed assembly of nano-objects. These parameters are reviewed explicitly in this report and their contributions are discussed.