Epidemiological perspectives on type 1 diabetes in childhood and adolescence in germany: 20 years of the Baden-württemberg Diabetes Incidence Registry (DIARY)
- PMID: 19903753
- PMCID: PMC2809277
- DOI: 10.2337/dc09-1503
Epidemiological perspectives on type 1 diabetes in childhood and adolescence in germany: 20 years of the Baden-württemberg Diabetes Incidence Registry (DIARY)
Abstract
Objective: To predict the frequency of type 1 diabetes in childhood and adolescence (<15 years of age) in Germany for the next 20 years.
Research design and methods: Data on diabetes onset has been collected by means of a registry in the federal German state of Baden-Württemberg (documentation period, 1987-2006; n = 5,108; completeness of data 98.1%).
Results: The current incidence rate (2000-2006) is 19.4 per 100,000 per year (95% CI 18.6-20.2). The annual incidence rate can be expressed as a square of a linear function of the calendar year X [y = (3.05 + 0.0778 x {X-1986})(2); r(2) = 0.90]. The highest increase per year was observed in the age-groups comprising 2- and 3-year-olds (12 and 13% per year, respectively). The incidence rate for the year 2026 is estimated to be 37.9 per 100,000 per year (95% CI 33.3-42.9).
Conclusions: The increase that we found in younger children is characteristic of a left shift toward an earlier age.
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References
-
- Green A, Gale EAM, Patterson CC. Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE Study. Lancet 1992; 339: 905– 909 - PubMed
-
- Ehehalt S, Blumenstock G, Willasch AM, Hub R, Ranke MB, Neu A. Continuous rise in incidence of childhood type 1 diabetes in Germany. Diabet Med 2008; 25: 755– 757 - PubMed
-
- LaPorte RE, McCarty D, Bruno G, Tajima N, Baba S. Counting diabetes in the next millennium: application of capture-recapture technology. Diabetes Care 1993; 16: 528– 534 - PubMed
-
- Green A, Patterson CCon behalf of the EURODIAB TIGER Study Group. Trends in the incidence of childhood-onset diabetes in Europe 1989–1998. Diabetologia 2001; 44: B3– B8 - PubMed
-
- Onkamo P, Väänänen S, Karvonen M, Tuomilehto J. Worldwide increase in incidence of type I diabetes: the analysis of the data on published incidence trends. Diabetologia 1999; 42: 1395– 1403 - PubMed
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