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Case Reports
. 2009 Sep;76(9):950-1.
doi: 10.1007/s12098-009-0190-2. Epub 2009 Nov 4.

Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy

Ozlem Engiz  1 , Merih Berberoglu, Zeynep Siklar, Pelin Bilir, Gonul Ocal
Affiliations
Case Reports

Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy

Ozlem Engiz et al. Indian J Pediatr. 2009 Sep.

Abstract

Functional follicular ovarian cysts are frequently reported in girls with peripheral precocious puberty (PP). These cysts are usually self-limiting and resolve spontaneously. Several drugs like antiestrogens (tamoxifen) and new aromatase inhibitors are seldom used for treatment. Here we report a girl with peripheral PP who presented with unilateral enlargement of the ovary and a recurrent autonomous ovarian cyst. No skin pigmentation or bone anomaly was noted. The patient was successfully treated with anastrozole, a highly selective aromatase inhibitor. No adverse reaction was noted. Anastrozole is a safe and tolerable drug especially used to suppress estrogen action.

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